Withania aka Ashwagundha the "Rejuvenator "

Withania somnifera aka Ashwagundha, you might also hear this herb referred to as “winter cherry”. This herb right here is one of my favourites (not my absolute fav but it’s up there).

I just love it, it does so much for you and we are going to explore some of that, right here right now. It has been used in Ayurvedic medicine for thousands of years. This herb is particularly great for all you stress heads out there… you know who you are ;)

In Ayurvedic medicine it is said about this herb:

“That which has the smell of a horse, as it gives the vitality and sexual energy of a horse”

So if you want to have the strength and virility (aphrodisiac/sexual energy) of a horse haha this might be the herb you want ;)

Withania aka Ashwagandha has been used for centuries in india as it is a traditional Aryuvedic herb

Withania aka Ashwagandha has been used for centuries in india as it is a traditional Aryuvedic herb

Now this herb is commonly referred to as an “adaptogen” or adaptogenic herb. But what does that mean?

Though this word is a relatively new concept to western medicine, China and Eastern medical theory has employed their use for centuries. Adaptogenic herbs improve the body’s adaptability, enabling the body to avoid reaching a point of collapse or over-stress. Adaptogens can have an overall tonifying effect or provide benefit within specific organ such as the circulatory, respiratory, digestive, reproductive and nervous systems.

The core of their action appears to be in helping the body deal with the physiology of stress. When we’re unable to cope with external pressures it leads to internal repercussions, and the manifestation of illness can develop in many diverse forms. Adaptogens seem to increase the threshold of resistance to damage through supporting the adrenal glands and possibly pitutiary gland function. Their normalizing effect leads to contradictory actions depending on the body’s needs. The restorative quality of these herbs is a unique feature of herbal medicine unlike any in the pharmaceutical index.

Adaptogens are capable of restoring normal tone and function to the HPA (hypothalamic/pituitary/adrenal) axis and SAS (sympathoadrenal system) and therefore to the entire body. As the adrenal glands underlie much of the body’s response to external and internal stressors. While improving resistance to stress they help to prevent some of the more common symptoms of stress including poor concentration, sleep disturbance, fatigue, decreased immune response, and decreased resistance to infections. Pretty amazing right?

What is it used for?

Withania is used to restore health to the nervous system and eases stress and mental exhaustion as it promotes mental clarity and improves memory and stamina. As a tonic for the elderly and to promote growth in children and enhance athletic performance, it also promotes recovery after illness and during convalescence and has great use in various chronic diseases involving inflammation. It will aid bone degeneration, rheumatism, joint pain and neuralgias and can be used topically for wounds and swelling. It also assists with reproductive health, general tonic, rejuvenating, nervous system tonic, sedative, immuno-modulator, anti-tumor, anti-inflammatory, astringent, anti-anemic, aphrodisiac and oxytocin. Not only that but it has been shown to have neuroprotective characteristics. One little herb that does so much!

Energetics of the herb

It is said to be bitter, astringent, sweet and heating. It decreases Vata and Kapha and increases Pitta and Ama (toxins) if used in excess. It is a Rasayana karma (rejuvenating tonic)- Rasa (essence) ayana(enter). It holds a similar place in Ayurvedic medicine as Ginseng does in Chinese medicine. It is a really rejuvenating herb for the muscles, marrow and semen (hence why it is thought of typically as a herb used in men). It was particularly used in people with a Vata constitution traditionally.

Traditionally it can be taken as a decoction to which may be added honey, raw sugar, pippali and basmati rice. It is said to inhibit ageing and catalyse the anabolic processes in the body. As a Rasayana karma herb it is used to rebuild mind-body, prevent decay and postpone ageing. They do not “add to the bulk” of the body tissues but increase the quality of them. They are subtle, specific and longer lasting that simple nutritive tonics. They sustain optimal form and function of various organs.

Said to be “Sattvic” in quality it is one of the best herbs for the mind and is clarifying and nurturing. It is calming and promotes deep, dreamless sleep.

But what are the benefits?

Stress, Fatigue and Anxiety

Our lives today are filled with stressors, emotional, physical, mental etc. Therefore this puts pressure on our HPA axis (Hypothalamic Pituitary) and can then cause dysfunction of this. Sometime you will hear people call this “adrenal fatigue”, but that’s not quite accurate. (see blog on stress/ anxiety and HPA axis)

If your body is under long term stress, this causes your adrenals to be under constant pressure to secrete cortisol, adrenaline (epinephrine), noradrenaline (norepinephrine) etc. With this constant messaging, your brain and adrenals begin miscommunicating, which can throw off your HPA-axis. 

Because Ashwagandha is an adaptogen:

  • it works through your HPA-axis (how your brain and adrenals communicate), and can therefore help balance how much cortisol your body makes. Making it have a significant anti-stress activity.

  • There have also been studies to show that Ashwagandha helps prevent the depletion of cortisol and vitamin C (which is highly concentrated in the adrenal glands) in the adrenals following a stressful event.

It has also been shown particularly in mice studies to reduce obsessive compulsive behaviours and typically being known as a nervine it is nourishing and thus protective to the nervous system from stress.

It’s a great herb to take before bedtime to help you reduce the “wired but tired” feeling so you get a better night’s rest, particularly due to its effects on GABA.

How does it help?

  • It can  modulate GABA neurotransmission and having low GABA is linked to stress and anxiety . Furthermore the potent sitoindosides and acylsterylglucosides within ashwagandha are well-known anti-stress agents.

  • These effects make it have a anxiolytic (which means it can be used to manage anxiety) action. Ashwagandha is beneficial for those with anxiety and chronic stress because it helps the body regulate cortisol and stress hormone output.  

  • Helps regulate the nervous system and cause it to have a more parasympathetic state that leads to deep restoration of the entire system. For this reason it is used for exhaustion, fatigue, insomnia from stress and neurasthenia (nervous exhaustion)

Evidence of this

  • 52 subjects suffering from chronic stress were given ashwagandha and assessed at the end of eight weeks. Across all measures, including serum cortisol levels, the Perceived Stress Scale and the Oxford Happiness QuestionInaire, significant improvements were shown (4)

  • In a small, randomized double-blind placebo-controlled study, benefits were observed after 60 days of continuous Ashwagandha use at a dose of 300 mg twice daily.

Sexual function/ hormonal balance

Withania is also known as an aphrodisiac and was typically thought of as a male tonic.

  • It increases testosterone in men- as the adrenal glands are responsible for DHEA production which is then converted to testosterone. and thus can increase motivation, mood and libido. It increases sperm count, sperm mobility and thus male fertility.

But it is very useful in both sexes:

  • This herb has been shown to improve orgasms, arousal, lubrication and sexual satisfaction. How good is that! It helps balance oestrogen and prolactin. When adrenals are in good shape then progesterone production continues on happily and enhances libido (esp in women).

Nootropic/brain function

Stress can cause degeneration (breakdown) of brain cells, which can lead to various neurological problems and diseases. Withania increases glutathione- which is an antioxidant in our bodies. Antioxidants protect us from free radical damage that causes ageing. It can also boost memory, concentration and has shown some beneifts in dementia and Parkinson’s disease.

Promotes neurite outgrowth which can allow greater connections between thought/ideas- better connections leads to better cognition. It also increases Ach (Acetylcholine) production in the brain, which is linked to memory and learning.

It increases dopamine, which is your feel good neurotransmitter that is also important for attention, sexual interest etc.

Cholesterol

When cortisol is chronically elevated, it can lead to high cholesterol, triglycerides, and blood sugar. Due to this herbs balancing action the adrenals it can therefore asset with lowering LDL cholesterol, triglycerides and blood glucose levels and increase HDL your good cholesterol.

Cancer

As Withania is an antioxidant as discussed above it can help with tumor growth and cancer treatment by preventing the spread of cancer cells in the body. This is not to say that this herb should replace the medical care or advice from your doctor. It is not a replacement for cancer drugs or other treatments. It may, however, be a helpful adjunct therapy and worth mentioning to your doctor/pharmacist to make sure it doesn’t interact with your other therapies.

Also it helps lower stress as discussed which can be beneficial when people are going through cancer and the stress of cancer treatment. It also helps reduce chemo-induced suppression of the immune system.
It is good to use this herb like a prophylactic agent to prevent cancer. It can be used in women on the oral contraceptive pill (OCP) to help reduce the risk of breast cancer etc.

Stablise sugar

Withania contains flavonoids which can lower blood sugar levels and decrease insulin resistance. By lowering blood glucose levels you are also reducing inflammation overall in the body.

Thyroid function

A well-functioning Ovarian-Adrenal-Thyroid Axis (OAT) is vital in the pursuit of balanced hormones. If our adrenal gland is overburdened and making lots of cortisol this mens that the thyroid and ovaries will struggle too. So by Withania lowering cortisol and balancing the adrenal it will therefore inadvertently help with thyroid function.
It can also help with hypothyroidism seperate to this process. It improves both TSH and T4, assisting an underactive thyroid. But as it is stimulating on the thyroid it is best avoided in hyperthyroidism unless managed by your doctor/practitioner.

Physical performance

Withania increases physical performance and the ability to endure under fatiguing conditions such as exercise, lifting weights and muscle recovery. Usage is linked to lower body fat percentages and strengthens the immune system to aid physical performance. So these effects make it good for athletes and those that exercise rigorously.

Boost Immunity

Chronic stress can eventually lead to a compromised immune system. Your lymphocytes (the white blood cells ) decrease and with chronic stress there is chronic inflammation, leading to a compromised immune system also. Withania can help increase the production of immunoglobulins and suppress inflammatory cytokines.  One way to know if your adrenals are under stress is to look at how often you are getting sick. Frequent colds or flus shows an immune system under stress.

Are there any precautions or reasons i could not take this herb?

Certain autoimmune conditions could be made worse for some people who take Withania or adaptogens in general (e.g. lupus), but this isn't true for everyone. In fact, some autoimmune conditions improve with the use of adaptogens. It's always good to chat with your practitioner if you have an autoimmune condition and are considering this herb.   

  • It might cause problems for people with hyperthyroidism because it can stimulate an already over-stimulated thyroid gland

  • Since it is in the nightshade family, those with nightshade sensitivities should be cautious*

  • Should not be used in pregnant women (even though traditionally it was used in “weak pregnant women” to stabilise the foetus)

  • It also lowers blood pressure so if you stuffer from orthostatic hypotension this might not be ideal for you.

  • Caution of use if on HRT (hormone replacement therapy) and if taking thyroid medications, do not start taking without checking with your doctor/pharmacist/ naturopath due to potential interactions.

How long until it takes affect, I want my stress gone now?

Effects can be seen right away but it also has effects longer term after 2-3months. If you have had chronically high stress, you can’t expect the effects of that to disappear over night as it didn’t occur overnight. So be patient. Plus remember herbs just like medications are not a silver bullet. You need to look at all the other factors such as diet etc that maybe impacting your health and contributing to stress for example.

Who is this good for?

Well anyone suffering from any of the conditions/ looking for the benefits listed above. But also athletes, students, busy parents, corporate workers etc.

You can see why this is one of my favourite herbs it can be used in a tincture mixed up from a practitioner, it is available in tablet forms and also in teas. So have a chat to your qualified herbalist, naturopath, pharmacist or doctor if you are wanting to use this herb and want to know if it will be right for you

xo Courtney

Courtney Dixon